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Add to EdgeTheraAgent: Self-Improving Therapeutic Agent for Precise and Comprehensive Treatment Planning
May 07, 2026
Formulating a treatment plan is inherently a complex reasoning and refinement task rather than a simple generation problem. However, existing large language models (LLMs) mainly rely on one-shot output without explicit verification, which may result in rough, incomplete, and potentially unsafe treatment plans. To address these limitations, we propose TheraAgent, an agentic framework that replaces one-shot generation with an iterative generate-judge-refine pipeline. By mirroring the actual reasoning process of human experts who iteratively revise treatment plans, our framework progressively transforms coarse and incomplete drafts into precise, comprehensive, and safer therapeutic regimens. To facilitate the critical judge component, we introduce TheraJudge, a treatment-specific evaluation module integrated into the inference loop to enforce clinical standards. Experiments show TheraAgent achieves state-of-the-art results on HealthBench, leading in Accuracy and Completeness. In expert evaluations, it attains an 86% win rate against physicians, with superior Targeting and Harm Control. Moreover, the highly agreement between TheraJudge and HealthBench evaluations confirms the reliability of our framework.
Trustworthy Federated Label Distribution Learning under Annotation Quality Disparity
May 06, 2026Label Distribution Learning (LDL) models supervision as an instance-wise probability distribution, enabling fine-grained learning under inherent ambiguity, but its success relies on high-fidelity label distributions that are costly to obtain and thus often noisy. Motivated by privacy-sensitive applications, we study Federated Label Distribution Learning (Fed-LDL), where data isolation further induces heterogeneous annotation quality across clients, making local updates unevenly reliable and breaking sample-size-based aggregation (e.g., FedAvg). To address this trust dilemma, we propose FedQual, a quality-aware Fed-LDL framework with two coupled mechanisms: (i) quality-adaptive client training guided by a global semantic anchor that calibrates low-quality clients while preserving high-quality autonomy, and (ii) reliability-aware server aggregation that reweights client contributions by effective reliable information rather than raw sample size. To enable rigorous evaluation, we construct four new Fed-LDL benchmarks (FER-LDL, FI-LDL, PIPAL-LDL, and KADID-LDL) with controlled annotation quality disparity. We further provide a theoretical guarantee showing that under heterogeneous supervision quality, client-specific calibration is strictly better than any uniform calibration. Extensive experiments on the proposed benchmarks demonstrate the effectiveness of FedQual.
CARD: Coarse-to-fine Autoregressive Modeling with Radix-based Decomposition for Transferable Free Energy Estimation
May 04, 2026Estimating free energy differences quantifies thermodynamic preferences in molecular interactions, which is central to chemistry and drug discovery. Despite fruitful progress, existing methods still face key limitations: classical computational approaches remain prohibitively expensive due to their reliance on extensive molecular dynamics simulations, while deep learning-based methods are constrained by either less-expressive generative models or input dimensions tied to a specific system, resulting in negligible generalization. To address these challenges, we propose CARD, a generative framework that employs a novel radix-based decomposition to bijectively convert 3D coordinates into mixed discrete-continuous sequences, enabling coarse-to-fine autoregressive modeling with enhanced expressiveness. Notably, the model corresponds to a distribution with zero free energy, serving as a proposal for absolute free energy computation of arbitrary systems without relying on alchemical pathways. Experiments across diverse tasks demonstrate that CARD matches the accuracy of classical computational methods on unseen systems with diverse topologies, while achieving an approximately 40-fold speedup in inference.
Benchmarking and Improving GUI Agents in High-Dynamic Environments
Apr 28, 2026Recent advancements in Graphical User Interface (GUI) agents have predominantly focused on training paradigms like supervised fine-tuning (SFT) and reinforcement learning (RL). However, the challenge of high-dynamic GUI environments remains largely underexplored. Existing agents typically rely on a single screenshot after each action for decision-making, leading to a partially observable (or even unobservable) Markov decision process, where the key GUI state including important information for actions is often inadequately captured. To systematically explore this challenge, we introduce DynamicGUIBench, a comprehensive online GUI benchmark spanning ten applications and diverse interaction scenarios characterized by important interface changes between actions. Furthermore, we present DynamicUI, an agent designed for dynamic interfaces, which takes screen-recording videos of the interaction process as input and consists of three components: a dynamic perceiver, a refinement strategy, and a reflection. Specifically, the dynamic perceiver clusters frames of the GUI video, generates captions for the centroids, and iteratively selects the most informative frames as the salient dynamic context. Considering that there may be inconsistencies and noise between the selected frames and the textual context of the agent, the refinement strategy employs an action-conditioned filtering to refine thoughts to mitigate thought-action inconsistency and redundancy. Based on the refined agent trajectories, the reflection module provides effective and accurate guidance for further actions. Experiments on DynamicGUIBench demonstrate that DynamicUI significantly improves the performance in dynamic GUI environments, while maintaining competitive performance on other public benchmarks.
OmniVTG: A Large-Scale Dataset and Training Paradigm for Open-World Video Temporal Grounding
Apr 28, 2026Video Temporal Grounding (VTG), the task of localizing video segments from text queries, struggles in open-world settings due to limited dataset scale and semantic diversity, causing performance gaps between common and rare concepts. To overcome these limitations, we introduce OmniVTG, a new large-scale dataset for open-world VTG, coupled with a Self-Correction Chain-of-Thought (CoT) training paradigm designed to enhance the grounding capabilities of Multimodal Large Language Models (MLLMs). Our OmniVTG is constructed via a novel Semantic Coverage Iterative Expansion pipeline, which first identifies gaps in the vocabulary of existing datasets and collects videos that are highly likely to contain these target concepts. For high-quality annotation, we leverage the insight that modern MLLMs excel at dense captioning more than direct grounding and design a caption-centric data engine to prompt MLLMs to generate dense, timestamped descriptions. Beyond the dataset, we observe that simple supervised finetuning (SFT) is insufficient, as a performance gap between rare and common concepts still persists. We find that MLLMs' video understanding ability significantly surpasses their direct grounding ability. Based on this, we propose a Self-Correction Chain-of-Thought (CoT) training paradigm. We train the MLLM to first predict, then use its understanding capabilities to reflect on and refine its own predictions. This capability is instilled via a three-stage pipeline of SFT, CoT finetuning, and reinforcement learning. Extensive experiments show our approach not only excels at open-world grounding in our OmniVTG dataset but also achieves state-of-the-art zero-shot performance on four existing VTG benchmarks. Code is available at https://github.com/oceanflowlab/OmniVTG.
From Skill Text to Skill Structure: The Scheduling-Structural-Logical Representation for Agent Skills
Apr 28, 2026LLM agents increasingly rely on reusable skills, capability packages that combine instructions, control flow, constraints, and tool calls. In most current agent systems, however, skills are still represented by text-heavy artifacts, including SKILL{.}md-style documents and structured records whose machine-usable evidence remains embedded largely in natural-language descriptions. This poses a challenge for skill-centered agent systems: managing skill collections and using skills to support agent both require reasoning over invocation interfaces, execution structure, and concrete side effects that are often entangled in a single textual surface. An explicit representation of skill knowledge may therefore help make these artifacts easier for machines to acquire and leverage. Drawing on Memory Organization Packets, Script Theory, and Conceptual Dependency from Schank and Abelson's classical work on linguistic knowledge representation, we introduce what is, to our knowledge, the first structured representation for agent skill artifacts that disentangles skill-level scheduling signals, scene-level execution structure, and logic-level action and resource-use evidence: the Scheduling-Structural-Logical (SSL) representation. We instantiate SSL with an LLM-based normalizer and evaluate it on a corpus of skills in two tasks, Skill Discovery and Risk Assessment, and superiorly outperform the text-only baselines: in Skill Discovery, SSL improves MRR from 0.573 to 0.707; in Risk Assessment, it improves macro F1 from 0.744 to 0.787. These findings reveal that explicit, source-grounded structure makes agent skills easier to search and review. They also suggest that SSL is best understood as a practical step toward more inspectable, reusable, and operationally actionable skill representations for agent systems, rather than as a finished standard or an end-to-end mechanism for managing and using skills.
FlashOverlap: Minimizing Tail Latency in Communication Overlap for Distributed LLM Training
Apr 27, 2026The rapid growth in the size of large language models has necessitated the partitioning of computational workloads across accelerators such as GPUs, TPUs, and NPUs. However, these parallelization strategies incur substantial data communication overhead significantly hindering computational efficiency. While communication-computation overlap presents a promising direction, existing data slicing based solutions suffer from tail latency. To overcome this limitation, this research introduces a novel communication-computation overlap technique to eliminate this tail latency in state of the art overlap methods for distributed LLM training. The aim of this technique is to effectively mitigate communication bottleneck of tensor parallelism and data parallelism for distributed training and inference. In particular, we propose a novel method termed Flash-Overlap that replaces conventional collective operations of reduce-scatter and all-gather with decomposed peer-to-peer (P2P) communication and schedules partitioned computations to enable fine-grained overlap. Our method provides an exact algorithm for reducing communication overhead that eliminates tail latency. Moreover, it presents a versatile solution compatible with data-parallel training and various tensor-level parallelism strategies, including TPSP and UP. Experimental evaluations demonstrate that our technique consistently achieves lower latency, superior Model FLOPS Utilization (MFU), and high throughput.
OmniFit: Multi-modal 3D Body Fitting via Scale-agnostic Dense Landmark Prediction
Apr 23, 2026Fitting an underlying body model to 3D clothed human assets has been extensively studied, yet most approaches focus on either single-modal inputs such as point clouds or multi-view images alone, often requiring a known metric scale. This constraint is frequently impractical, especially for AI-generated assets where scale distortion is common. We propose OmniFit, a method that can seamlessly handle diverse multi-modal inputs, including full scans, partial depth observations, and image captures, while remaining scale-agnostic for both real and synthetic assets. Our key innovation is a simple yet effective conditional transformer decoder that directly maps surface points to dense body landmarks, which are then used for SMPL-X parameter fitting. In addition, an optional plug-and-play image adapter incorporates visual cues to compensate for missing geometric information. We further introduce a dedicated scale predictor that rescales subjects to canonical body proportions. OmniFit substantially outperforms state-of-the-art methods by 57.1 to 80.9 percent across daily and loose clothing scenarios. To the best of our knowledge, it is the first body fitting method to surpass multi-view optimization baselines and the first to achieve millimeter-level accuracy on the CAPE and 4D-DRESS benchmarks.
Exploring Spatial Intelligence from a Generative Perspective
Apr 22, 2026Spatial intelligence is essential for multimodal large language models, yet current benchmarks largely assess it only from an understanding perspective. We ask whether modern generative or unified multimodal models also possess generative spatial intelligence (GSI), the ability to respect and manipulate 3D spatial constraints during image generation, and whether such capability can be measured or improved. We introduce GSI-Bench, the first benchmark designed to quantify GSI through spatially grounded image editing. It consists of two complementary components: GSI-Real, a high-quality real-world dataset built via a 3D-prior-guided generation and filtering pipeline, and GSI-Syn, a large-scale synthetic benchmark with controllable spatial operations and fully automated labeling. Together with a unified evaluation protocol, GSI-Bench enables scalable, model-agnostic assessment of spatial compliance and editing fidelity. Experiments show that fine-tuning unified multimodal models on GSI-Syn yields substantial gains on both synthetic and real tasks and, strikingly, also improves downstream spatial understanding. This provides the first clear evidence that generative training can tangibly strengthen spatial reasoning, establishing a new pathway for advancing spatial intelligence in multimodal models.
UDM-GRPO: Stable and Efficient Group Relative Policy Optimization for Uniform Discrete Diffusion Models
Apr 21, 2026Uniform Discrete Diffusion Model (UDM) has recently emerged as a promising paradigm for discrete generative modeling; however, its integration with reinforcement learning remains largely unexplored. We observe that naively applying GRPO to UDM leads to training instability and marginal performance gains. To address this, we propose UDM-GRPO, the first framework to integrate UDM with RL. Our method is guided by two key insights: (i) treating the final clean sample as the action provides more accurate and stable optimization signals; and (ii) reconstructing trajectories via the diffusion forward process better aligns probability paths with the pretraining distribution. Additionally, we introduce two strategies, Reduced-Step and CFG-Free, to further improve training efficiency. UDM-GRPO significantly improves base model performance across multiple T2I tasks. Notably, GenEval accuracy improves from $69\%$ to $96\%$ and PickScore increases from $20.46$ to $23.81$, achieving state-of-the-art performance in both continuous and discrete settings. On the OCR benchmark, accuracy rises from $8\%$ to $57\%$, further validating the generalization ability of our method. Code is available at https://github.com/Yovecent/UDM-GRPO.